Tottenham are much harder to beat under Mauricio Pochettino but back Liverpool striker Daniel Sturridge to strike first in a 1-1 draw.
Home advantage means Leicester could spring a surprise on Arsene Wenger's Arsenal, with Leonardo Ulloa bagging first in a 2-1 success.
It won't be a goal-fest at Villa Park tomorrow so back the hosts to edge it against Hull 1-0 courtesy of an Andreas Weimann strike.
Swansea will be confident of making it three league wins from three with Gylfi Sigurdsson tipped to open the scoring in a 3-1 victory.
Graziano Pelle got off the mark against Millwall and is set to open the scoring for Saints but West Ham will battle back to a 2-2 draw.
Striker Conor Wickham will give the Black Cats a flying start with his first goal of the season in a 2-2 draw at QPR tomorrow.
Emmanuel Riviere will open his account for Newcastle as the £5million French striker scores the game's only goal against Palace..
Sergio Aguero will open the scoring with his third league goal in as many matches as City run out convincing 3-0 winners over Stoke..
Expect a close encounter as both sides maintain their unbeaten starts to the season with a 1-1 draw - Diego Costa opening the scoring.
Robin van Persie will set United on their way with his first goal of the season in their first three-point haul with a 2-0 victory..
Manchester City should have enough to see off Liverpool’s challenge and midfielder Yaya Toure is a good bet to fire them to a 1-0 win.
Louis van Gaal's sticky start will continue as Adam Johnson picks up where he left off, scoring first for the Black Cats in a 1-1 draw.
Erik Lamela will grab his first goal for Spurs in resounding 3-0 win over QPR as Harry Redknapp’s return to White Hart Lane turns sour.
With Europa League to contend with Hull's attention will be elsewhere, allowing Stoke to claim 3-1 win, Marko Arnautovic scoring first.
Expect Swansea to emerge victorious in this battle of young English managers against Burnley, Gylfi Sigurdsson inspiring a 2-1 win.
Expect Graziano Pelle, prolific in Eredivisie, scoring 50 times in 57 appearances, to get off the mark here in 2-0 win for Southampton.
Back this to be another 2-2 draw for Everton, with Belgian duo Kevin Mirallas and Romelu Lukaku grabbing a goal each against Arsenal.
With a squad galvanised by adversity, Palace will claim a 2-0 win over West Ham, with Jason Puncheon looking good bet to open scoring.
Leicester face a baptism of fire and it should be a comfortable home win for Chelsea, with Diego Costa opening scoring in 3-0 success.