Sergio Aguero struck all four goals against Tottenham and will strike first in a hard-fought 2-1 City victory at Upton Park tomorrow.
In-form Saido Berahino will be on the score sheet again as West Brom edge to a 2-1 win over Crystal Palace on Saturday afternoon..
Back in-form Wilfried Bony to find the back of the net for Swansea but expect Leicester to come back and earn a 1-1 draw tomorrow.
Back Danny Welbeck to maintain his good start for Arsenal by opening the scoring against his former club Sunderland in a 2-1 victory.
Graziano Pelle is currently justifying his £8million summer move to Southampton and will open scoring in a 2-0 home win over Stoke..
Abel Hernandez has hit three goals in five appearances for Hull and will open the scoring in an entertaining 2-2 draw with Liverpool.
Man Utd's resurgence will continue here, with Radamel Falcao making it two in two with the opener at the Hawthorns in a 3-1 success.
This is unlikely to be a classic but back Peter Crouch to continue his decent form against Swansea with only goal in 1-0 win for Stoke.
Harry Redknapp's QPR are unlikely to end a poor run here, so back Jordan Henderson to open the scoring for Liverpool in a 2-1 victory.
Expect the Saints to get back to winning ways here as Dusan Tadic breaks the deadlock in a convincing 3-1 success against Sunderland.
Toon boss Alan Pardew is desperate for a win and he will get one so go for a hard-fought 1-0 victory and Remy Cabella to score first..
City were 6-0 winners in this fixture last term and will again ease to victory, but go for a steady 3-1, with Edin Dzeko netting first.
The home side will not have this one all their own way, so expect a 1-1 draw with Andreas Weimann opening the scoring for Villa..
Expect a comfortable victory for Chelsea at Crystal Palace, with Eden Hazard again breaking the deadlock in another 2-0 success..
The Hammers will rectify their poor away form with a narrow 2-1 victory at Burnley, with the returning Kevin Nolan breaking deadlock..
This one could be closer than you think, so go for a 2-1 victory for the Gunners and Danny Welbeck to open the scoring against Hull.
In-form striker Diafra Sakho has netted four goals in his last five matches and will open scoring in 2-1 win for West Ham against QPR.
Striker Graziano Pelle has five goals to his name already this season and is a decent shout to net Southampton's opener in a 1-1 draw.
Radamel Falcao is yet to score for United and could get off the mark here only for their defence to let them down again in 1-1 draw.